Cell-free (cf) DNA extraction from biofluids commonly produces low yields with larger processing volumes. The MAGicBead cfDNA isolation kit addresses this challenge using unique, magnetic bead surface chemistry which facilitates unparalleled cfDNA recovery, with reduced binding buffer volumes. Without the need for a bead drying step, the MAGicBead cfDNA isolation kit streamlines the DNA extraction process, providing high-quality cfDNA which is NGS-ready.
Benefits of using the MAGicBead cfDNA isolation kit
• High yield cfDNA isolation
• Compatible with up to 10mL plasma
• Produces NGS-ready, enzymatic inhibitor-free cfDNA
• Compatible with all open automation platforms
• Alcohol-free workflow
• Minimal binding buffer volumes
• No bead air-dry
• Custom option available
The MAGicBead cfDNA isolation kit has a simple, scaleable & quick protocol which is easily adapted for any automation platform
MAGicBead cfDNA isolation kit sample compatibility
| Sample types | Blood tube types (plasma) | Automation platforms | Incompatible |
|---|---|---|---|
| Plasma Serum Saliva Urine Cerebrospinal fluid Amniotic fluid Spent cell culture media |
K2EDTA Streck-DNA K3EDTA Na2EDTA Na-Citrate Na-F / K-Oxalate |
KingFisher™ Flex/Apex (Thermo Fisher) Fluent® X (Tecan) Microlab® STAR™ (Hamilton) OT-2 (Opentrons) |
Heparin Synovial fluid |
Achieve the highest cfDNA yields MAgicBead technology
Plasma cfDNA was extracted using three different magbead-based kits. Total cfDNA yields were assessed using Qubit™ 1x dsDNA HS Assay Kit (Thermo-Fisher Scientific).
Material available to download
MAGicBead cfDNA isolation kit brochure
KingFisher is a registered trademark of Thermo Fisher Scientific Oy.
Fluent is a registered trademark of Tecan Trading AG.
Microlab STAR is a registered trademark of Hamilton Company.
Products
Note: product availability depends on country - see product detail page.
| Details | Cat number & supplier | Size | Price |
| MAGicBead cfDNA Isolation Kit D4086 · Zymo Research | D4086 Zymo Research |
50 preps |
£891.00
50 preps
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| MAGicBead™ cfDNA Elution Buffer D4086-5-2 · Zymo Research | D4086-5-2 Zymo Research |
2 ml |
£21.00
2 ml
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