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Cell lines for drug discovery

Cell line engineering experts BPS Bioscience offer a selection of unique products perfectly designed for CAR-T research, such as a collection of TCR, B2M, and CIITA knockout cell lines to model potentially universal CAR-T cells. Additionally, cell lines expressing common CAR targets are also available, many of which include the luciferase reporter for simple monitoring.

BPS Bioscience also provide stable cell lines expressing validated surface proteins, engineered to enable several other research applications, such as inhibitor/activator studies, pathway analysis and high-throughput screening systems.

Benefits of using BPS Bioscience cell lines
• >200 cell lines
• Stable for up to 10 passages
• Vigorously tested
• Carefully selected
• Each vial contains at least one million cells
• Custom cell reporter systems available

Available cell line formats:

Cell line format Uses
Reporter cell lines •    Test activation or inhibition of a cellular pathway using high throughput screening
•    Measure signalling, promoter and transcription factor activities
•    >20 available cell lines
•    >70 available reporter systems
Co-stimulatory cell lines •    Inhibitor screening
•    Antibody affinity
•    Co-culture studies
Overexpression/knockout cell lines •    Screen antibodies or compounds against a given gene
•    Available for ion channel studies, GPCR screens, and metabolite-based assays
•    Varying expression levels to mimic different stages of cancer target cells
CAR-T reporter cell lines •    CAR engineering optimisation
•    Compound/Ab screening
•    CAR-T signaling research
•    Screening donor variations


All BPS Bioscience cell lines have been extensively validated, confirming biological activity when appropriate. Detailed protocols are included with instructions for general cell culture and maintenance. Each cell line is tested for viability and mycoplasma prior to shipping, ensuring valid and reproducible results while minimising the need for end-user optimisation and troubleshooting. 

Custom cell line development
With their cell line development services, BPS Bioscience can engineer cell lines with a knocked-out protein, stably expressing proteins at high, homogenous levels, or bearing reporter constructs.

Materials for download:
BPS cell systems brochure

Products

Note: product availability depends on country - see product detail page.

Details Cat number & supplier Size Price
BCMA CHO Recombinant Cell Line (High Expression) BPS-79500-H · BPS Bioscience
BPS-79500-H
BPS Bioscience
2 vials £7239.00
2 vials
view
SLAMF7 (CS1) CHO Recombinant Cell Line (High Expression) BPS-79608-H · BPS Bioscience
BPS-79608-H
BPS Bioscience
2 vials £7239.00
2 vials
view
CD37/CHO Recombinant Cell Line (High Expression) BPS-79607-H · BPS Bioscience
BPS-79607-H
BPS Bioscience
2 vials £6894.00
2 vials
view
CD47 - HEK293 Cell Line BPS-71249 · BPS Bioscience
BPS-71249
BPS Bioscience
2 vials £7372.00
2 vials
view
PD-L1 - CHO Recombinant Cell Line BPS-60543 · BPS Bioscience
BPS-60543
BPS Bioscience
2 vials £5521.00
2 vials
view
CD20 - CHO Recombinant Cell Line (High Expression) BPS-79624-H · BPS Bioscience
BPS-79624-H
BPS Bioscience
2 vials £7584.00
2 vials
view
ROR1-CHO Recombinant Cell Line BPS-79609-H · BPS Bioscience
BPS-79609-H
BPS Bioscience
2 vials £7966.00
2 vials
view
CD38 - CHO Recombinant Cell Line (High Expression) BPS-79615-H · BPS Bioscience
BPS-79615-H
BPS Bioscience
2 vials £7817.00
2 vials
view
BCMA CHO Recombinant Cell Line (Low Expression) BPS-79500-L · BPS Bioscience
BPS-79500-L
BPS Bioscience
2 vials £7239.00
2 vials
view
ERBB2-CHO Recombinant Cell Line (Low Expression) BPS-79612-L · BPS Bioscience
BPS-79612-L
BPS Bioscience
2 vials £7584.00
2 vials
view
CD19 CHO Recombinant Cell Line (Medium Expression) BPS-79561-M · BPS Bioscience
BPS-79561-M
BPS Bioscience
2 vials £7584.00
2 vials
view
CD19 CHO Recombinant Cell Line (Low Expression) BPS-79561-L · BPS Bioscience
BPS-79561-L
BPS Bioscience
2 vials £7584.00
2 vials
view
CD22 CHO Recombinant Cell Line (High Expression) BPS-79557-H · BPS Bioscience
BPS-79557-H
BPS Bioscience
2 vials £7584.00
2 vials
view
CD19 CHO Recombinant Cell Line (High Expression) BPS-79561-H · BPS Bioscience
BPS-79561-H
BPS Bioscience
2 vials £7584.00
2 vials
view
ERBB2-CHO Recombinant Cell Line (Low Expression) BPS-79612-M · BPS Bioscience
BPS-79612-M
BPS Bioscience
2 vials £7584.00
2 vials
view