Acid Sensing Cell Lines
Cambridge Bioscience, through our collaboration with B'SYS, offers access to a range of stably replicating, validated acid sensing channel cell lines including:
ASIC1a (long/short), ASIC1b
Gene Name: ACCN2
Description: The human ACCN2 gene encodes the pore-forming subunit of ASIC1a, a proton-activated, channel permeable to both Na+ and Ca2+ ions. ASIC1a channels widely expressed in the neurons of peripheral sensory and the central nervous system are therapeutic targets in pain and neurodegenerative diseases.
Gene Name: ACCN1
Description: The human ACCN1 gene encodes the pore-forming subunit of ASIC2a, a proton-activated, Na+-permeable channel. ASIC2a channels widely expressed in sensory neurons of the peripheral and central nervous systems are therapeutic targets in pain and neurodegenerative diseases.
Gene Name: ACCN3
Description: The human ACCN3 gene encodes the pore-forming subunit of ASIC3, a proton-activated, Na+-permeable channel. ASIC3 channels expressed primarily in dorsal root ganglion neurons are therapeutic targets in pain and inflammation.
Find Out More
To discuss the purchase of an acid sensing channel cell line or our custom screening services, please contact our B'SYS specialist Here