Supplier information: Bethyl Laboratories

Since 1972, Bethyl has provided quality polyclonal antibody products and services for both clinical and research applications.

To ensure the quality of their antibodies, all antibodies are produced and affinity purified by antigen specific affinity chromatography. They continue to identify new and emerging proteins of interests, producing antibodies to these new proteins, as well as those classic proteins for which there is a dearth of quality antibodies.

Bethyl antibodies are validated in a wide range of applications including ELISA, western blot, immunoprecipitation, immunohistochemistry and immunocytochemistry.

New from Bethyl Laboratories, an ELISA kit for the detection of Human Lactoferrin in EDTA plasma, urine, and milk. The kit contains sufficient components to quantitate Human Lactoferrin protein concentration in up to 40 samples, tested in duplicate. The range of the Human Lactoferrin ELISA is 1.56-100 ng/ml.

Please click here for a copy of the kit protocol.

Cambridge Bioscience can also provide a range of Lactoferrin antibodies and peptides.

The involvement of G-protein signaling in a wide variety of cellular activities has resulted in the study GTPases and their regulators as therapeutic targets in a number of human diseases. The regulation of GTPase signaling is highly and carefully regulated and hundreds of GTPase regulators have been identified.

GTPase Activity

Studies of mTOR (mammalian target of rapamycin) have demonstrated that it performs an essential role in integrating cellular signals received from growth factors and from the detection of nutrient, stress, and energy levels in the cell.
The integration of signals by mTOR functions to control cell growth by influencing cellular processes such as translation initiation, ribosome biogenesis, and transcription factor localization.

Bethyl have a range of Polyclonal Antibodies to Proteins in the mTOR Pathway.

Bethyl Laboratories quantitative ELISA kits contain an affinity purified antibody, calibrator and HRP conjugate. Each kit contains reagents sufficient for 1000 single well assays.
These kits do not include plates, buffers or substrate. If these components are not readily available in your lab, you may want to order an ELISA Starter Accessory Kit, Cat No. E101 or Cat No. E103.

Please click here to request your 2009 Bethyl catalogue.

CHD3, CHD7 & CHD9/CReMM are members of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interact with nucleosomes and play a role in chromatin remodeling to modulate transcription.

The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain.

For further information please click here

Protein-protein interactions provide a source of complexity for the multitude of physiological processes that must be executed by eukaryotes for development and for the maintenance of homeostasis. Through their conserved beta propeller structure, WD-repeat-containing proteins contribute to this source of complexity and have thus established themselves as a critical subject of study.

For further information, please click here