This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
186452-09-5
Purity:
99.74
Molecular Weight:
360.45
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GPI-1046 is a immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in PFC and NAc-core. GPI-1046 is an analog of FK506, which is an immunophilin ligand that has been shown neuroprotective effects in neurodegenerative disease models[1]. GPI-1046 readily crosses the blood-brain barrier and promotes the regeneration of dopamine (DA) cells in the CNS in association with functional recovery in rodent models[2]. GPI-1046 improves HIV-associated injury of peripheral nerves[3].
Storage Temperature:
4°C (Powder, protect from light)