This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1505515-69-4
Purity:
99.78
Molecular Weight:
551.61
Alternative Names:
DS-6051b; AB-106; IBI-344
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Taletrectinib (DS-6051b) is a potent, orally active, and next-generation selective ROS1/NTRK inhibitor. Taletrectinib potently inhibits recombinant ROS1, NTRK1, NTRK2, and NTRK3 with IC50s of 0.207, 0.622, 2.28, and 0.98 nM, respectively. Taletrectinib also inhibits ROS1 G2032R and other Crizotinib-resistant ROS1 mutants[1][2].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)