This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1352914-52-3
Purity:
98.36
Molecular Weight:
507.53
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
CR-1-31-B is a synthetic rocaglate and a potent eIF4A inhibitor. CR-1-31-B exhibits powerful inhibitory effects over eIF4A by perturbing the interaction between eIF4A and RNA, sequentially impeding initiation during protein synthesis. CR-1-31-B perturbs association of Plasmodium falciparum eIF4A (PfeIF4A) with RNA. CR-1-31-B induces apoptosis of neuroblastoma and gallbladder cancer cells[1][2][3][4].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)