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Iptacopan

Catalogue number:
HY-127105-100mg
Supplier:
Size:
100 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1644670-37-0

Purity:

99.93

Molecular Formula:

C25H30N2O4

Molecular Weight:

422.52

Mass Spectrometry:

Reference Materials

Alternative Names:

LNP023

Product Description:

Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G)[1][2].