This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2408648-20-2
Purity:
99.63
Molecular Weight:
353.38
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
BO-264 is a highly potent and orally active transforming acidic coiled-coil 3 (TACC3) inhibitor with an IC50 of 188 nM and a Kd of 1.5 nM. BO-264 specifically blocks the function of FGFR3-TACC3 fusion protein. BO-264 induces spindle assembly checkpoint (SAC)-dependent mitotic arrest, DNA damage and apoptosis. BO-264 has broad-spectrum antitumor activity[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)