Palbociclib-propargyl
Catalogue number:
HY-130296-100mg
Supplier:
Size:
100 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2366269-23-8
Purity:
95.23
Molecular Weight:
485.58
Alternative Names:
PROTAC CDK6 ligand 1
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Palbociclib-propargyl is a ligand for target protein CDK6 for PROTAC, and binds to CRBN ligand via a PEG linker to make a PROTAC CP-10. CP-10 shows a DC50 of 2.1 nM for CDK6[1]. Palbociclib-propargyl is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Storage Temperature:
-20°C (Powder, stored under nitrogen)