K-Ras ligand-Linker Conjugate 4
Catalogue number:
HY-130822-1mL
Supplier:
Size:
1 ml _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2378261-83-5
Purity:
95.06
Molecular Weight:
697.82
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
K-Ras ligand-Linker Conjugate 4 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 4 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells[1].
Storage Temperature:
-20°C (Powder, stored under nitrogen)