This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2114339-57-8
Purity:
99.59
Molecular Weight:
554.48
Alternative Names:
SAR439859
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
SAR439859 (compound 43d) is an orally active, nonsteroidal and selective estrogen receptor degrader (SERD). SAR439859 is a potent ER antagonist and has ER degrading activity with an EC50 of 0.2 nM for ERα degradation[1]. SAR439859 demonstrates robust antitumor efficacy and limited cross-resistance in ER+ breast cancer[2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)