This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
24418-86-8
Purity:
98.09
Molecular Weight:
254.24
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC50 of 2 µM for GST-hSK. SKI V potently inhibits PI3K with an IC50 of 6 µM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)