This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1276121-88-0
Purity:
99.93
Molecular Weight:
374.46
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PF-3644022 is a potent, selective, orally active and ATP-competitive MAPKAPK2 (MK2) inhibitor with an IC50 of 5.2 nM and a Ki of 3 nM. PF-3644022 also inhibits MK3 and p38 regulated/activated kinase (PRAK) with IC50s of 53 nM and 5.0 nM, respectively. PF-3644022 potently inhibits TNFα production and has anti-inflammatory effect[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)