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K-Ras ligand-Linker Conjugate 5

Catalogue number:
HY-130823-100mg
Supplier:
Size:
100 mg _$$_
Product is available in:
  • UK
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£1118.00 Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2378261-85-7

Purity:

96.96

Molecular Formula:

C42H59N7O8

Molecular Weight:

789.96

Product Description:

K-Ras ligand-Linker Conjugate 5 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 5 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells[1].

Storage Temperature:

-20°C (Powder, stored under nitrogen)

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