This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1352879-65-2
Purity:
98.44
Molecular Formula:
C27H27N3O2
Molecular Weight:
425.52
Alternative Names:
PF-74
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PF-3450074 (PF-74) is a specifical inhibitor of HIV-1 capsid protein (CA) and displays a broad-spectrum inhibition of HIV isolates with submicromolar potency (EC50=8-640 nM). PF-3450074 (PF-74) acts at an early stage of HIV-1 infection, inhibits viral replication by directly competing with the binding of CPSF6 and NUP153, and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle[1][2]. CPSF6: nuclear host factors cleavage and polyadenylation specific factor 6; NUP153: nucleoporin 153.
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)