1-Naphthohydroxamic acid
Catalogue number:
HY-130538-50mg
Supplier:
Size:
50 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
6953-61-3
Purity:
99.72
Molecular Formula:
C11H9NO2
Molecular Weight:
187.19
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 µM. 1-Naphthohydroxamic acid is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 µM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity[1][2].1-Naphthohydroxamic acid can induce tubulin acetylation[3].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)