This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1846570-31-7
Purity:
99.27
Molecular Weight:
478.63
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
CM-272 is a first-in-class, potent, selective, substrate-competitive and reversible dual G9a/DNA methyltransferases (DNMTs) inhibitor with antitumor activities. CM-272 inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP with IC50s of 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing IFN-stimulated genes and immunogenic cell death[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)