Tos-PEG4-t-butyl ester
Catalogue number:
HY-130422-100mg
Supplier:
Size:
100 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
217817-01-1
Purity:
97.44
Molecular Weight:
432.53
Alternative Names:
Tos-PEG4-Boc
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker, which refers to the PEG composition. Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) can be used in the synthesis of a series of PROTACs, such as BI-3663 (HY-111546). BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation, and inhibits PTK2 with an IC50 of 18 nM[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)