This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
615538-51-7
Purity:
95
Molecular Weight:
550.01
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
DC0-NH2 is an effector moiety for ADC and a simplified analog of DC1 with better stability. DC0-NH2 is about 1000-fold more cytotoxic than commonly used anticancer agents (ex. Doxorubicin). DC0-NH2 can bind to the minor groove of DNA, followed by alkylation of adenine residues by its propabenzindole (CBI) component[1].
Storage Temperature:
-20°C (Powder, stored under nitrogen)