This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2134169-43-8
Purity:
99.68
Molecular Weight:
636.73
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
MI-3454 is an orally active, highly potent and selective menin-MLL1 interaction inhibitor with an IC50 of 0.51 nM. MI-3454 inhibits proliferation, induces differentiation and complete remission or regression of leukemia in mouse models of MLL1-rearranged or NPM1-mutated leukemia through downregulation of key genes involved in leukemogenesis[1].
Storage Temperature:
4°C (Powder, stored under nitrogen)