Desmethylglycitein
Catalogue number:
HY-N5072-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
17817-31-1
Purity:
98.98
Molecular Weight:
270.24
Alternative Names:
4',6,7-Trihydroxyisoflavone
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity[1]. Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1)[2]. Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes[3].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)