J-113863
Catalogue number:
HY-103360-1ml
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
353791-85-2
Purity:
99
Molecular Weight:
655.44
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
J-113863 is a potent and selective CCR1 antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively. J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect[1][2][3].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)