Hck-IN-1
Catalogue number:
HY-125028-1ml
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1473404-51-1
Purity:
98.53
Molecular Weight:
402.81
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Hck-IN-1 (compound B9), a diphenylpyrazolo compound, is a selective Nef-dependent Hck inhibitor with IC50s of 2.8 µM, >20 µM for Nef:Hck complex and Hck, respectively. Hck-IN-1 is a direct and wide HIV-1 Nef antagonists with an IC50 of 100-300 nM for wild-type HIV-1 replication. Hck-IN-1 binds pocket residue Asn126 and has anti-retroviral activity[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)