ZLDI-8
Catalogue number:
HY-123931-1ml
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
667880-38-8
Purity:
98.78
Molecular Weight:
433.52
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
ZLDI-8 is a Notch activating/cleaving enzyme ADAM-17 inhibitor and inhibits the cleavage of Notch protein. ZLDI-8 decreases the expression of pro-survival/anti-apoptosis and epithelial-mesenchymal transition (EMT) related proteins. ZLDI-8 is also a competitive and irreversible tyrosine phosphatase (Lyp) inhibitor with an IC50 of 31.6 µM and a Ki of 26.22 µM. ZLDI-8 inhibits the growth of MHCC97-H cells with an IC50 of 5.32 µM[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)