GNF4877
Catalogue number:
HY-129492-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2041073-22-5
Purity:
99.32
Molecular Weight:
494.52
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GNF4877 is a potent DYRK1A and GSK3β inhibitor with IC50s of 6 nM and 16 nM, respectively, which leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation (EC50 of 0.66 µM for mouse β (R7T1) cells)[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)