PG01
Catalogue number:
HY-103369-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
853138-65-5
Purity:
98
Molecular Weight:
439.55
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PG01 is a potent CFTR Cl- channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K, G970R and G551D (CFTR mutants) with Kd values of 0.22 µM, 0.45 µM and 1.94 µM, respectively. PG01 is also effective on ΔF508 (Ka of 0.3 µM). PG01 increases ΔF508-CFTR Cl- current after adding Forskolin[1][2].
Storage Temperature:
-20°C, 3 years (Powder)