This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2375840-87-0
Purity:
99.94
Molecular Weight:
453.84
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM. NDI-091143 inhibits ACLY catalysis allosterically, by stabilizing large conformational changes in the citrate domain that indirectly block the binding and recognition of citrate[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)