Semapimod (tetrahydrochloride)
Catalogue number:
HY-15509A-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
164301-51-3
Purity:
98.43
Molecular Weight:
890.74
Alternative Names:
CNI-1493; CPSI-2364 (tetrahydrochloride)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Semapimod tetrahydrochloride (CNI-1493), an inhibitor of proinflammatory cytokine production, can inhibit TNF-α, IL-1β, and IL-6. Semapimod tetrahydrochloride inhibits TLR4 signaling (IC50≈0.3 µM). Semapimod tetrahydrochloride inhibits p38 MAPK and nitric oxide production in macrophages. Semapimod tetrahydrochloride has potential in a variety of inflammatory and autoimmune disorders[1][2][3].
Storage Temperature:
-20°C (Powder, sealed storage, away from moisture and light)