PROTAC Bcl2 degrader-1
Catalogue number:
HY-125876-1mg
Supplier:
Size:
1 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2378801-85-3
Purity:
98.78
Molecular Weight:
941.84
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC based on Cereblon ligand, which potently and selectively induces the degradation of Bcl-2 (IC50, 4.94 µM; DC50, 3.0 µM) and Mcl-1 (IC50, 11.81 µM) by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1/Bcl-2 dual inhibitor Nap-1[1].
Storage Temperature:
-20°C (Powder, stored under nitrogen)