This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1247018-19-4
Purity:
99.64
Molecular Weight:
510.63
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT-1, respectively. FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors[1].
Storage Temperature:
4°C (Powder, stored under nitrogen)