This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1026785-55-6
Purity:
99.92
Molecular Weight:
445.6147
Alternative Names:
VX-222
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo-initiated RNA synthesis[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)