This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
393121-74-9
Purity:
99.89
Molecular Weight:
255.31
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
AA147 is a endoplasmic reticulum (ER) proteostasis regulator. AA147 promotes protection against oxidative damage in neuronal cells and prevents endothelial barrier dysfunction by activating ATF6 arm (selectively) of the unfolded protein response (UPR) and the NRF2 oxidative stress response. AA147 can rebalances XBP1s expression in vivo, and also induces survival motor neuron (SMN) expression and spinal motorneuron (MN) protection[1][2][3][4].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)