This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
18200-13-0
Purity:
99.88
Molecular Weight:
291.35
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
BL-1249 is a nonsteroidal anti-inflammatory agent (NSAID) and a potassium channel activator. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC50 values of 5.5 µM and 8.0 µM, respectively. BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 µM) than vascular tissue (EC50 of 21.0 µM)[1][2].
Storage Temperature:
-20°C, 3 years (Powder)