This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1644670-37-0
Purity:
99.96
Molecular Weight:
422.52
Alternative Names:
LNP023
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G)[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)