This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
450839-40-4
Purity:
98.18
Molecular Weight:
504.46
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
ABT-100 is a potent, highly selective and orally active farnesyltransferase inhibitor. ABT-100 inhibits cell proliferation (IC50s of 2.2 nM, 3.8 nM, 5.9 nM, 6.9 nM, 9.2 nM, 70 nM and 818 nM for EJ-1, DLD-1, MDA-MB-231, HCT-116, MiaPaCa-2, PC-3, and DU-145 cells, respectively), increases apoptosis and decreases angiogenesis. ABT-100 possesses broad-spectrum antitumor activity[1].
Storage Temperature:
-20°C (Powder, protect from light)