This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
147076-36-6
Purity:
99.76
Molecular Weight:
310.27
Alternative Names:
HR325
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)