This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2753348-63-7
Purity:
99.38
Molecular Weight:
628.6
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
EGFR-IN-1 TFA is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. EGFR-IN-1 TFA potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 TFA displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity[1].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)