This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2437475-16-4
Purity:
99.08
Molecular Weight:
458.39
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
T6167923 is a selective inhibitor of MyD88-dependent signaling pathways. T6167923 directly binds to Toll/IL1 receptor (TIR) domain of MyD88 and disrupts MyD88 homodimeric formation. T6167923 inhibits NF-κB driven Staphylococcus enterotoxin AP (SEAP) activity, and improves anti-inflammatory activity with IC50s of 2.7 µM, 2.9 µM, 2.66 µM and 2.66 µM for IFN-γ, IL-1β, IL-6 and TNF-α, respectively[1][2].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)