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Thalidomide-propargyl

Catalogue number:
HY-126457-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2098487-39-7

Purity:

99.97

Molecular Weight:

312.28

Product Description:

Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-propargyl can be connected to the ligand for protein by a linker to form the IMiD containing PROTACs[1]. Thalidomide-propargyl is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Storage Temperature:

-20°C, 3 years; 4°C, 2 years (Powder)

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