This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2387510-80-5
Purity:
99.21
Molecular Weight:
464.56
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
MRK-740 is a potent, selective and substrate-competitive PRDM9 histone methyltransferase inhibitor with an IC50 of 80 nM. MRK-740 is more selective for PRDM9 than other histone methyltransferases and other non-epigenetic targets. MRK-740 reduces PRDM9-dependent trimethylation of H3K4 (IC50 = 0.8 µM)[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)