This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1003019-41-7
Purity:
99.63
Molecular Formula:
C22H21F3N6
Molecular Weight:
426.44
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GNF362 is a selective, potent, and orally bioavailable inhibitor of inositol trisphosphate 3’ kinase B (Itpkb) with an IC50 of 9 nM. GNF362 also inhibits Itpka and Itpkc with IC50 values of 20 nM and 19 nM, respectively. Inositol trisphosphate 3’ kinase B (Itpkb) is a Ca2+-dependent kinase, which phosphorylates the 3’ position of Ins (1,4,5) P3 to generate inositol 1,3,4,5-tetrakisphosphate [Ins (1,3,4,5) P4][1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)