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DM4-SMe

Catalogue number:
HY-130082-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£615.00 Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

796073-68-2

Purity:

98

Molecular Formula:

C39H56ClN3O10S2

Molecular Weight:

826.46

Product Description:

DM4-SMe is a metabolite of antibody-maytansin conjugates (AMCs) and a tubulin inhibitor, and also a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM4-SMe inhibits KB cells with an IC50 of 0.026 nM[1][2].

Storage Temperature:

-20°C, 3 years (Powder)

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