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BPN-15606

Catalogue number:
HY-117482-1ml
Supplier:
Size:
1 ml _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£411.00 Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1914989-49-3

Purity:

99.96

Molecular Formula:

C23H23FN6O

Molecular Weight:

418.47

Product Description:

BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN-15606 lowers Aβ42 and Aβ40 levels in the central nervous system of rats and mice. BPN-15606 has acceptable PK/PD properties, including bioavailability, half-life, and clearance[1].

Storage Temperature:

-20°C (Powder, stored under nitrogen)

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