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RO2959 (hydrochloride)

Catalogue number:
HY-113618A-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
  • UK
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£435.00 Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1219927-22-6

Purity:

98

Molecular Formula:

C21H19F2N5OS.xHCl

Product Description:

RO2959 hydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 hydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1/Stim1 channels with an IC50 of 25 nM. RO2959 hydrochloride is also a potent inhibitor of human IL-2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways[1][2].

Storage Temperature:

4°C (Powder, sealed storage, away from moisture)

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