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NDI-091143

Catalogue number:
HY-127111-5mg
Supplier:
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2375840-87-0

Purity:

99.94

Molecular Formula:

C20H14ClF2NO5S

Molecular Weight:

453.84

Product Description:

NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM. NDI-091143 inhibits ACLY catalysis allosterically, by stabilizing large conformational changes in the citrate domain that indirectly block the binding and recognition of citrate[1].

Storage Temperature:

-20°C, 3 years; 4°C, 2 years (Powder)

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