This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
906439-72-3
Purity:
99.23
Molecular Formula:
C18H15NOS
Molecular Weight:
293.38
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
COH34 is a potent and specific poly(ADP-ribose) glycohydrolase (PARG) inhibitor with an IC50 of 0.37 nM. COH34 binds to the catalytic domain of PARG (Kd=0.547 µM), thereby prolonging PARylation at DNA lesions and trapping DNA repair factors[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)