This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2664214-60-0
Purity:
99.28
Molecular Formula:
C30H38N8O2
Molecular Weight:
542.68
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
BI-4020 is a fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor. BI-4020 inhibits not only the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines) but also the double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM). BI-4020 also shows activity against EGFR wt (IC50=190 nM). BI-4020 shows high kinome selectivity and good DMPK properties[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)