This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1386162-69-1
Purity:
99.5
Molecular Formula:
C22H25N3O3
Molecular Weight:
379.45
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
ML417 is a selective and brain penetrant D3 dopamine receptor (D3R) agonist, with an EC50 of 38 nM. ML417 potently promotes D3R-mediated β-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)