This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
73340-41-7
Purity:
99.64
Molecular Formula:
C17H16O5
Molecular Weight:
300.31
Alternative Names:
Astrapterocarpan
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus, inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 µM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade[1].
Storage Temperature:
4°C (Powder, protect from light)